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Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and proposals for monitoring. Testosterone alternative in hypogonadal men with angina improves ischaemic threshold and quality of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone improve human platelet thromboxane A2 receptor density and aggregation responses.
Geolocation Api
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Privateness Detection Api
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with conventional cardiac danger elements using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, likely secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the right coronary artery. Physicians and patients ought to pay attention to the clinical penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
Moreover, a part of endothelial dysfunction has been proposed, which can contribute to irregular vessel reactivity. However, testosterone in physiologic doses may even be helpful in sufferers with angina , have greater ischemic thresholds and improved quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood circulate in men with established coronary artery disease . Therefore, an interplay of endogenous elements of the patient’s threat profile as well as the testosterone dosing could also be problems with whether opposed occasions happen.
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Erythrocytosis has been reported as a potential effect of testosterone, which could be useful in patients with anemia. The greatest risk of erythrocytosis occurs with injectable types camslda of testosterone compared with transdermal preparations, particularly in supraphysiologic doses. An improve of up to 44% of the baseline hematocrit has been reported .
Discussion And Review Of The Literature
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